https://www.tellmeproject.eu/taxonomy/term/24/all en https://www.tellmeproject.eu/content/mutated-strain-h7n9-flu-virus-developed-drug-resistance <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>A strain of the emergent avian influenza A(H7N9) virus, which is now circulating in China, has developed some kind of resistance to antiviral drugs without losing its virulence. These are the conclusion exposed in an <a href="http://www.nature.com/ncomms/2013/131210/ncomms3854/full/ncomms3854.html">article just published on <em>Nature Communications</em></a> by a group of researchers from the Icahn School of Medicine at Mount Sinai.</p><p>They found that some H7N9 clinical isolates had an amino acid substitution in the structure of the viral neuraminidase (NA), a membrane-expressed, glycosylated enzyme to which the haemagglutinin (HA) glycoprotein binds.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/antivirals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Antivirals</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Wed, 11 Dec 2013 10:31:54 +0000 amministratore 231 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/mutated-strain-h7n9-flu-virus-developed-drug-resistance <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>A strain of the emergent avian influenza A(H7N9) virus, which is now circulating in China, has developed some kind of resistance to antiviral drugs without losing its virulence. These are the conclusion exposed in an <a href="http://www.nature.com/ncomms/2013/131210/ncomms3854/full/ncomms3854.html">article just published on <em>Nature Communications</em></a> by a group of researchers from the Icahn School of Medicine at Mount Sinai.</p><p>They found that some H7N9 clinical isolates had an amino acid substitution in the structure of the viral neuraminidase (NA), a membrane-expressed, glycosylated enzyme to which the haemagglutinin (HA) glycoprotein binds.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/antivirals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Antivirals</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Wed, 11 Dec 2013 10:31:54 +0000 amministratore 231 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/mutated-strain-h7n9-flu-virus-developed-drug-resistance <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>A strain of the emergent avian influenza A(H7N9) virus, which is now circulating in China, has developed some kind of resistance to antiviral drugs without losing its virulence. These are the conclusion exposed in an <a href="http://www.nature.com/ncomms/2013/131210/ncomms3854/full/ncomms3854.html">article just published on <em>Nature Communications</em></a> by a group of researchers from the Icahn School of Medicine at Mount Sinai.</p><p>They found that some H7N9 clinical isolates had an amino acid substitution in the structure of the viral neuraminidase (NA), a membrane-expressed, glycosylated enzyme to which the haemagglutinin (HA) glycoprotein binds.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/antivirals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Antivirals</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Wed, 11 Dec 2013 10:31:54 +0000 amministratore 231 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/mutated-strain-h7n9-flu-virus-developed-drug-resistance <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>A strain of the emergent avian influenza A(H7N9) virus, which is now circulating in China, has developed some kind of resistance to antiviral drugs without losing its virulence. These are the conclusion exposed in an <a href="http://www.nature.com/ncomms/2013/131210/ncomms3854/full/ncomms3854.html">article just published on <em>Nature Communications</em></a> by a group of researchers from the Icahn School of Medicine at Mount Sinai.</p><p>They found that some H7N9 clinical isolates had an amino acid substitution in the structure of the viral neuraminidase (NA), a membrane-expressed, glycosylated enzyme to which the haemagglutinin (HA) glycoprotein binds.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/antivirals" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Antivirals</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Wed, 11 Dec 2013 10:31:54 +0000 amministratore 231 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/bird-flu-vaccine-adjuvant-approved-fda <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>An adjuvanted vaccine against influenza A (H5N1) virus has been approved by the US Food and Drug Administration (FDA). The vaccine, Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted, also referred to as Q-Pan H5N1, has been tested for safety by comparing approximately 3,400 adults 18 years of age and older who received the vaccine to about 1,100 adults who received placebo. This product was produced by a Canadian subsidiary of GlaxoSmithKline Biologicals and is intended for use in people 18 years of age and older who are at increased risk of exposure to the H5N1 influenza virus.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vaccine</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/h5n1" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H5N1</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Tue, 26 Nov 2013 19:57:13 +0000 amministratore 230 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/bird-flu-vaccine-adjuvant-approved-fda <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>An adjuvanted vaccine against influenza A (H5N1) virus has been approved by the US Food and Drug Administration (FDA). The vaccine, Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted, also referred to as Q-Pan H5N1, has been tested for safety by comparing approximately 3,400 adults 18 years of age and older who received the vaccine to about 1,100 adults who received placebo. This product was produced by a Canadian subsidiary of GlaxoSmithKline Biologicals and is intended for use in people 18 years of age and older who are at increased risk of exposure to the H5N1 influenza virus.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vaccine</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/h5n1" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H5N1</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Tue, 26 Nov 2013 19:57:13 +0000 amministratore 230 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/bird-flu-vaccine-adjuvant-approved-fda <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>An adjuvanted vaccine against influenza A (H5N1) virus has been approved by the US Food and Drug Administration (FDA). The vaccine, Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted, also referred to as Q-Pan H5N1, has been tested for safety by comparing approximately 3,400 adults 18 years of age and older who received the vaccine to about 1,100 adults who received placebo. This product was produced by a Canadian subsidiary of GlaxoSmithKline Biologicals and is intended for use in people 18 years of age and older who are at increased risk of exposure to the H5N1 influenza virus.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vaccine</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/h5n1" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H5N1</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Tue, 26 Nov 2013 19:57:13 +0000 amministratore 230 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/bird-flu-outbreak-poultry-farm-ferrara-italy <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>An outbreak of a highly pathogenic avian influenza virus struck a commercial farm of layer hens near Ferrara, Italy. The farmer timely informed about suspect clinical signs, thus allowing the detection of the disease. The diagnostic tests were performed by the Experimental Zooprophylactic Institute and by the National Laboratory in Padua, and revealed that the virus belong to the H7 subtype, whilst further diagnostic examination to determine its N type are ongoing.</p><p>A protection zone of 3 km and a surveillance zone of 10 km have been established around the farm, which is under restriction.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/infectious-disease-outbreak" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Infectious disease outbreak</a></div></div></div> Sat, 17 Aug 2013 08:09:19 +0000 amministratore 206 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/bird-flu-outbreak-poultry-farm-ferrara-italy <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>An outbreak of a highly pathogenic avian influenza virus struck a commercial farm of layer hens near Ferrara, Italy. The farmer timely informed about suspect clinical signs, thus allowing the detection of the disease. The diagnostic tests were performed by the Experimental Zooprophylactic Institute and by the National Laboratory in Padua, and revealed that the virus belong to the H7 subtype, whilst further diagnostic examination to determine its N type are ongoing.</p><p>A protection zone of 3 km and a surveillance zone of 10 km have been established around the farm, which is under restriction.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/infectious-disease-outbreak" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Infectious disease outbreak</a></div></div></div> Sat, 17 Aug 2013 08:09:19 +0000 amministratore 206 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/new-information-transmission-modalities-h7n9-virus <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>A team from the University of Hong Kong evaluated the infectivity of the H7N9 avian flu virus, discovering some relevant issues. First of all, it came out that, although there was no evidence of sustained human-to-human transmission, H7N9 may infect pigs, thus proving to be transmissible in mammals. By combining with pig viruses, new variants can be generated and this could represent a potential danger. Also, the bird flu virus that is now circulating in China can be transmitted through airborne exposure and not only by close contact with infected individuals.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Tue, 28 May 2013 16:33:50 +0000 amministratore 197 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/new-information-transmission-modalities-h7n9-virus <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>A team from the University of Hong Kong evaluated the infectivity of the H7N9 avian flu virus, discovering some relevant issues. First of all, it came out that, although there was no evidence of sustained human-to-human transmission, H7N9 may infect pigs, thus proving to be transmissible in mammals. By combining with pig viruses, new variants can be generated and this could represent a potential danger. Also, the bird flu virus that is now circulating in China can be transmitted through airborne exposure and not only by close contact with infected individuals.</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Tue, 28 May 2013 16:33:50 +0000 amministratore 197 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/viewpoint-h7n9-vaccination <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Michael Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota, a professor in the School of Public Health, and an adjunct professor in the University of Minnesota Medical School. He is a recognized authority in the field of epidemiology and, in the past, he had criticized the lack of international preparedness for an influenza pandemic. In <a href="http://jama.jamanetwork.com/article.aspx?articleid=1686871">an article published on the Journal of the American Medical Association</a>, he and his colleagues examine several issues regarding the development of vaccines against the potential threat</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vaccine</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Fri, 10 May 2013 12:53:08 +0000 amministratore 185 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/viewpoint-h7n9-vaccination <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Michael Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota, a professor in the School of Public Health, and an adjunct professor in the University of Minnesota Medical School. He is a recognized authority in the field of epidemiology and, in the past, he had criticized the lack of international preparedness for an influenza pandemic. In <a href="http://jama.jamanetwork.com/article.aspx?articleid=1686871">an article published on the Journal of the American Medical Association</a>, he and his colleagues examine several issues regarding the development of vaccines against the potential threat</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vaccine</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Fri, 10 May 2013 12:53:08 +0000 amministratore 185 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/viewpoint-h7n9-vaccination <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Michael Osterholm is the director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota, a professor in the School of Public Health, and an adjunct professor in the University of Minnesota Medical School. He is a recognized authority in the field of epidemiology and, in the past, he had criticized the lack of international preparedness for an influenza pandemic. In <a href="http://jama.jamanetwork.com/article.aspx?articleid=1686871">an article published on the Journal of the American Medical Association</a>, he and his colleagues examine several issues regarding the development of vaccines against the potential threat</p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Vaccine</a></div><div class="field-item even" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Fri, 10 May 2013 12:53:08 +0000 amministratore 185 at https://www.tellmeproject.eu https://www.tellmeproject.eu/content/infographic-about-h7n9 <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p><span style="font-family: arial, sans-serif; font-size: 13px;">Jeremy Chui, a medical student at the Sheffield University, realized an <a href="http://news.ivulpes.com/h7n9/?goback=%252Egde_4945314_member_237057628">effective infographic</a> about the H7N9 avian flu virus now circulating in China. Data have been obtained from the World Health Organization, the Xinhua News Agency, Reuters and Forbes.</span></p></div></div></div><div class="field field-name-field-tags field-type-taxonomy-term-reference field-label-above"><div class="field-label">Tags:&nbsp;</div><div class="field-items"><div class="field-item even" rel="dc:subject"><a href="/tags/h7n9" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">H7N9</a></div><div class="field-item odd" rel="dc:subject"><a href="/tags/avianbird-flu" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Avian/Bird Flu</a></div></div></div> Mon, 06 May 2013 13:05:38 +0000 amministratore 184 at https://www.tellmeproject.eu